SCD5 (Center) Rabbit Polyclonal Antibody

CAT#: AP53809PU-N

SCD5 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SCD5 Antibody (Center) in MCF-7 cell line lysates (35 ug/lane). This demonstrates the SCD5 antibody detected the SCD5 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blotting: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of Human SCD5
• Specificity: Recognizes SCD5 (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens stearoyl-CoA desaturase 5 (SCD5), transcript variant 1
• Database Link:
  Entrez Gene 79966 Human
• Background: Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).
• Synonyms: Stearoyl-CoA desaturase 5, HSCD5, Acyl-CoA-desaturase 4, ACOD4, SCD4, Stearoyl-CoA 9-desaturase
• Note: Molecular Weight: 37610 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Biosynthesis of unsaturated fatty acids, PPAR signaling pathway