CAVIN2 (Center) Rabbit Polyclonal Antibody

CAT#: AP53824PU-N

CAVIN2 (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of SDR Antibody (Center) in CHO cell line lysates (35 ug/lane). SDR (arrow) was detected using the purified Pab.

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  Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded lung carcinoma stained with SDR Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

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  Flow Cytometric analysis of NCI-H460 cells using SDR Antibody (Center) (Bottom histogram) compared to a negative control cell (Top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Hamster, Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 115~145 amino acids from the Central region of Human SDR.
• Specificity: Recognizes SDR (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: serum deprivation response
• Database Link:
  Entrez Gene 8436 Human
  UniProt ID O95810
• Background: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
• Synonyms: Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein
• Note: Molecular Weight: 47173 Da