SEC61B (Center) Rabbit Polyclonal Antibody

CAT#: AP53833PU-N

SEC61B (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SEC61B Antibody (Center) in Mouse liver tissue lysates (35ug/lane). This demonstrates the SEC61B antibody detected the SEC61B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of Human SEC61B (NP_006799.1)
• Specificity: Recognizes SEC61B (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens Sec61 translocon beta subunit (SEC61B)
• Database Link:
  Entrez Gene 10952 Human
• Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
• Synonyms: SEC61B
• Note: Molecular Weight: 9974 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Vibrio cholerae infection