SECISBP2 (Center) Rabbit Polyclonal Antibody

CAT#: AP53835PU-N

SECISBP2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

western blot analysis of SECISBP2 Antibody (Center) in HL-60 cell line lysates (35ug/lane). This demonstrates the SECISBP2 antibody detected the SECISBP2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 500-530 amino acids from the Central region of Human SECISBP2
• Specificity: Recognizes SECISBP2 (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens SECIS binding protein 2 (SECISBP2), transcript variant 1
• Database Link:
  Entrez Gene 79048 Human
• Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
• Synonyms: SECIS-binding protein 2, SBP2
• Note: Molecular Weight: 95462 Da