LY108 (SLAMF6) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53926PU-N

LY108 (SLAMF6) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD352 / SLAMF6 Antibody (C-term) in T47D cell line lysates (35ug/lane). This demonstrates the SLAMF6 antibody detected the SLAMF6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of Human SLAMF6
• Specificity: This antibody recognizes Human CD352 / SLAMF6 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens SLAM family member 6 (SLAMF6), transcript variant 1
• Database Link:
  Entrez Gene 114836 Human
• Background: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Synonyms: LY108, KALI, Activating NK receptor, NK-T-B-antigen, NTB-A
• Note: Molecular Weight: 37345 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane