SPG7 (Center) Rabbit Polyclonal Antibody

CAT#: AP54017PU-N

SPG7 (Center) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution

Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Western blot: ~1/1000.
Enzyme immunoassay: 1/1000.

Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen Synthetic peptide - KLH conjugated corresponding to the central region (between 115-141aa) of Human Paraplegin / SPG7
Specificity This antibody recognizes Human Paraplegin / SPG7.
Other species not tested.
Formulation PBS with 0.09% (W/V) Sodium azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified through a Protein A column followed by peptide affinity purification
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 88235 Da (calculated)
Gene Name Homo sapiens SPG7, paraplegin matrix AAA peptidase subunit (SPG7), transcript variant 1
Background The SPG7 gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7.
Synonyms Spastic paraplegia 7 protein, CAR, CMAR, PGN
Reference Data
Protein Families Protease, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.