NCOA1 (Center) Rabbit Polyclonal Antibody

CAT#: AP54040PU-N

NCOA1 (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane) using NCOA1 / SRC1 antibody. This demonstrates the NCOA1 antibody detected the NCOA1protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/50-1/100.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 593-625aa) of human NCOA1 / SRC1.
• Specificity: This antibody recognizes NCOA1/SRC1.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens nuclear receptor coactivator 1 (NCOA1), transcript variant 1
• Database Link:
  Entrez Gene 8648 Human
• Background: The protein encoded by the NCOA1 gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: NCoA-1, Nuclear receptor coactivator 1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, NY-REN-52, BHLHE74
• Note: Molecular Weight: 156757 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors