SSRP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54054PU-N

SSRP1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SSRP1 / FACT80 Antibody (C-term) in CEM cell line lysates (35ug/lane). This demonstrates the SSRP1 antibody detected the SSRP1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of Human SSRP1.
• Specificity: This antibody recognizes Human SSRP1 / FACT80 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens structure specific recognition protein 1 (SSRP1)
• Database Link:
  Entrez Gene 6749 Human
• Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
• Synonyms: FACT complex subunit SSRP1, FACTp80, T160
• Note: Molecular Weight: 81075 Da

Reference Data

• Protein Families: Transcription Factors