AMSH (STAMBP) (C-term) Rabbit Polyclonal Antibody

CAT#: AP54063PU-N

AMSH (STAMBP) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in A549 cell line lysates (35 ug/lane) using STAMBP Antibody (C-term). This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).

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  Western blot analysis in Mouse cerebellum tissue lysates (35 ug/lane using STAMBP Antibody (C-term). This demonstrates the STAMBP antibody detected the STAMBP protein (arrow).

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  Formalin fixed, paraffin embedded human prostate carcinoma stained with STAMBP Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STAMBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 362-391 amino acids from the C-terminal region of Human STAMBP
• Specificity: This antibody recognizes Human and Mouse STAMBP (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens STAM binding protein (STAMBP), transcript variant 1
• Database Link:
  Entrez Gene 70527 MouseEntrez Gene 10617 Human
• Background:
  Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
• Synonyms: STAM-binding protein, AMSH
• Note: Molecular Weight: 48077 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis