STARD4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP54067PU-N

STARD4 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in human placenta tissue lysates (35ug/lane) using STARD4 Antibody (N-term). This demonstrates the STARD4 antibody detected the STARD4 protein (arrow).

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  Formalin fixed and paraffin embedded human kidney tissue stained with STARD4 Antibody (N-term) f ollowed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STARD4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemitry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of Human STARD4.
• Specificity: This antibody recognizes Human STARD4 (N-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens StAR related lipid transfer domain containing 4 (STARD4), transcript variant 1
• Database Link:
  Entrez Gene 134429 Human
• Background:
  Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
• Synonyms: STARD4
• Note: Molecular Weight: 23517 Da