Stanniocalcin 1 (STC1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP54070PU-N

Stanniocalcin 1 (STC1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in U251 cell line lysates (35ug/lane) using Stanniocalcin-1 / STC1 antibody. (C-term). This demonstrates the Stanniocalcin-1 antibody detected the Stanniocalcin-1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 192-221aa) of human Stanniocalcin-1.
• Specificity: This antibody recognizes Stanniocalcin-1 at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens stanniocalcin 1 (STC1)
• Database Link:
  Entrez Gene 6781 Human
• Background: The STC1 gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
• Synonyms: Stanniocalcin-1, STC-1, STC
• Note: Molecular Weight: 27621 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein