STK33 (N-term) Rabbit Polyclonal Antibody

CAT#: AP54076PU-N

STK33 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

STK33 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the STK33 antibody detected the STK33 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human STK33
• Specificity: This antibody recognizes Human STK33 at N-term.
  Other species not tested.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 57831 Da
• Gene Name: Homo sapiens serine/threonine kinase 33 (STK33), transcript variant 1
• Database Link:
  Entrez Gene 65975 Human
• Background: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. Contains 1 protein kinase domain.
  Function: Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for the survival of KRAS-dependent AML cell lines.
  Tissue Location: Highly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were observed in the following tissues: amygdala, aorta, esophagus, colon ascending, colon transverse, skeletal muscle, spleen, peripheral blood leukocyte, lymph node, bone marrow, placenta, prostate, liver, salivary gland, mammary gland, some tumor cell lines, fetal brain, fetal liver, fetal spleen and fetal thymus. No signal at all was detectable in RNA from tissues of the nervous system.
• Synonyms: Serine/threonine-protein kinase 33

Reference Data

• Protein Families: Druggable Genome, Protein Kinase