SYK (N-term) Rabbit Polyclonal Antibody

CAT#: AP54120PU-N

SYK (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

SYK Antibody western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the SYK antibody detected the SYK protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human MID1IP1
• Specificity: This antibody detects SYK at N-term.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage:

  Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens spleen tyrosine kinase (SYK), transcript variant 2
• Database Link:
  Entrez Gene 6850 Human
• Background:
  This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
• Synonyms: Tyrosine-protein kinase SYK, Spleen tyrosine kinase
• Note: Molecular Weight: 72066 Da

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity