TCF7L2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP54203PU-N

TCF7L2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TCF7L2 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35 ug/lane). This demonstrates the TCF7L2 antibody detected the TCF7L2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human TCF7L2
• Specificity: This antibody detects TCF7L2 (N-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transcription factor 7 like 2 (TCF7L2), transcript variant 1
• Database Link:
  Entrez Gene 21416 MouseEntrez Gene 6934 Human
• Background: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
• Synonyms: Transcription factor 7-like 2, T-cell-specific transcription factor 4, TCF4, TCF-4
• Note: Molecular Weight: 51kd Isoform 9. 67919 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Melanogenesis, Pathways in cancer, Prostate cancer, Thyroid cancer, Wnt signaling pathway