TGF beta 1 (TGFB1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP54230PU-N

TGF beta 1 (TGFB1) (N-term) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Other products for "TGFB1"

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blot: 1/1,000.
Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Immunofluorescence: 1/10-1/50.
Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of Human TGFB1.
Specificity This antibody detects TGF-beta-1 (TGFB1) (N-term).
Formulation PBS with 0.09% (W/V) Sodium Azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column followed by peptide affinity purification
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens transforming growth factor beta 1 (TGFB1)
Background TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Synonyms TGFB, Transforming growth factor beta-1, TGF-beta-1
Note Molecular Weight: 44341 Da
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transcription Factors
Protein Pathways Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.