TIFA (N-term) Rabbit Polyclonal Antibody

CAT#: AP54249PU-N

TIFA (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35 ug/lane). TIFA (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 52~79 amino acids from the N-terminal region of human TIFA
• Specificity: This antibody detects TIFA / T2BP (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TRAF interacting protein with forkhead associated domain (TIFA)
• Database Link:
  Entrez Gene 92610 Human
• Background: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
• Synonyms: TRAF2-binding protein
• Note: Molecular Weight: 21445 Da