TLE 1 (TLE1) (Center) Rabbit Polyclonal Antibody

CAT#: AP54266PU-N

TLE 1 (TLE1) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of TLE1 Antibody (Center) in Jurkat cell line lysates (35 ug/lane). TLE1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 199~228 amino acids from the Central region of human TLE1
• Specificity: This antibody detects TLE1 (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transducin like enhancer of split 1 (TLE1), transcript variant 2
• Database Link:
  Entrez Gene 7088 Human
• Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
• Synonyms: Transducin-like enhancer protein 1, ESG1
• Note: Molecular Weight: 83201 Da

Reference Data

• Protein Families: Transcription Factors