TNFAIP8 (N-term) Rabbit Polyclonal Antibody
Other products for "TNFAIP8"
Specifications
Product Data | |
Applications | FC, WB |
Recommended Dilution | WB; E. The suggested dilution is: ELISA ~~ 1:1;000 Western blotting~~ 1:100~500 |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | Immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human TNFAIP8 |
Formulation | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column; followed by peptide affinity purification. State: Aff - Purified |
Concentration | lot specific |
Gene Name | Homo sapiens TNF alpha induced protein 8 (TNFAIP8), transcript variant 2 |
Database Link | |
Background | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
Synonyms | SCC-S2, NDED, MDC-3.13 |
Note | Molecular Weight: 23003 Da |
Reference Data | |
Protein Families | Druggable Genome |
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