DcR3 (TNFRSF6B) (N-term) Rabbit Polyclonal Antibody
Other products for "TNFRSF6B"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:50~100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human TNFRSF6B |
Specificity | This antibody detects TNFRSF6B / DCR3 (N-term). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column followed by peptide affinity purification |
Storage | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens tumor necrosis factor receptor superfamily member 6b (TNFRSF6B) |
Database Link | |
Background | This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. |
Synonyms | Decoy receptor 3 |
Note | Molecular Weight: 32680 Da |
Reference Data | |
Protein Families | Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction |
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