DcR3 (TNFRSF6B) (N-term) Rabbit Polyclonal Antibody

CAT#: AP54313PU-N

DcR3 (TNFRSF6B) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TNFRSF6B Antibody (N-term) western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the TNFRSF6B antibody detected the TNFRSF6B protein (arrow).

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  TNFRSF6B antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF6B antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:50~100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human TNFRSF6B
• Specificity: This antibody detects TNFRSF6B / DCR3 (N-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: tumor necrosis factor receptor superfamily member 6b
• Database Link:
  Entrez Gene 8771 Human
  UniProt ID O95407
• Background: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
• Synonyms: Decoy receptor 3
• Note: Molecular Weight: 32680 Da

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction