CD252 (TNFSF4) (Center) Rabbit Polyclonal Antibody

CAT#: AP54316PU-N

CD252 (TNFSF4) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

TNFSF4 Antibody (Center) western blot analysis in K562 cell line lysates (35 ug/lane). This demonstrates the TNFSF4 antibody detected the TNFSF4 protein (arrow).

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  TNFSF4 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Flow cytometry: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human TNFSF4
• Specificity: This antibody detects CD252 / TNFSF4 (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tumor necrosis factor superfamily member 4 (TNFSF4), transcript variant 1
• Database Link:
  Entrez Gene 7292 Human
• Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
• Synonyms: TXGP1, OX40 ligand, OX40L, Glycoprotein Gp34
• Note: Molecular Weight: 21050 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction