TOR2A (Center) Rabbit Polyclonal Antibody

CAT#: AP54337PU-N

TOR2A (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

TOR2A Antibody (Center) western blot analysis in human placenta tissue lysates (35 ug/lane). This demonstrates the TOR2A antibody detected the TOR2A protein (arrow).

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  TOR2A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TOR2A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 201-229 amino acids from the Central region of human TOR2A
• Specificity: This antibody detects Torsin-2A (TOR2A) (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens torsin family 2 member A (TOR2A), transcript variant 1
• Database Link:
  Entrez Gene 27433 Human
• Background: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
• Synonyms: TORP1, Torsin-related protein 1
• Note: Molecular Weight: 35714 Da

Reference Data

• Protein Families: Secreted Protein, Transmembrane