TRPC4 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54360PU-N

TRPC4 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

TRPC4 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35 ug/lane). This demonstrates the TRPC4 antibody detected the TRPC4 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 811-840 amino acids from the C-terminal region of human TRPC4
• Specificity: This antibody detects TRPC4 / TRP4 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transient receptor potential cation channel subfamily C member 4 (TRPC4), transcript variant beta
• Database Link:
  Entrez Gene 7223 Human
• Background: Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.
• Synonyms: Trp-related protein 4, TRP-4, CCE1
• Note: Molecular Weight: 112101 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane