UBA52 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54434PU-N

UBA52 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

UBA52 Antibody (C-Term) western blot analysis in Hela cell line lysates (35 ug/lane). This demonstrates the UBA52 antibody detected the UBA52 protein (arrow).

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  UBA52 antibody (C-Term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UBA52 antibody (C-Term) for immunohistochemistry. Clinical relevance has not been evaluated.

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  UBA52 Antibody (C-Term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/100~1/500.
  Immunohistochemistry on Paraffin Sections: 1/50~1/100.
  Flow Cytometry: 1/10~1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 100-128 amino acids from the C-terminal region of human UBA52
• Specificity: This antibody detects UBA52 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ubiquitin A-52 residue ribosomal protein fusion product 1 (UBA52), transcript variant 1
• Database Link:
  Entrez Gene 7311 Human
• Background: Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.
• Synonyms: UBCEP2, CEP52
• Note: Molecular Weight: 14728 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Ribosome