UBE2D2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54437PU-N

UBE2D2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

UBE2D2 Antibody (C-term) western blot analysis in 293 cell line lysates (35 ug/lane). This demonstrates the UBE2D2 antibody detected the UBE2D2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2
• Specificity: This antibody detects UBE2D2 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ubiquitin conjugating enzyme E2 D2 (UBE2D2), transcript variant 1
• Database Link:
  Entrez Gene 7322 Human
• Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
• Synonyms: Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, UBC4, UBCH5B, E2(17)KB 2
• Note: Molecular Weight: 16735 Da

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis