UBE2D3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54438PU-N

UBE2D3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

UBE2D3 Antibody (C-term) western blot analysis in Hela cell line lysates (35 ug/lane). This demonstrates the UBE2D3 antibody detected the UBE2D3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human UBE2D3
• Specificity: This antibody detects UBE2D3 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ubiquitin conjugating enzyme E2 D3
• Database Link:
  Entrez Gene 7323 Human
  UniProt ID P61077
• Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
• Synonyms: UBC5C, UBCH5C
• Note: Molecular Weight: 16687 Da

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis