UQCRB (Center) Rabbit Polyclonal Antibody

CAT#: AP54480PU-N

UQCRB (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

UQCRB Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35 ug/lane). This demonstrates the UQCRB antibody detected the UQCRB protein (arrow).

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  UQCRB Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UQCRB Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human UQCRB
• Specificity: This antibody detects UQCRB (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ubiquinol-cytochrome c reductase binding protein (UQCRB), transcript variant 2
• Database Link:
  Entrez Gene 7381 Human
• Background: This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.
• Synonyms: UQBP, QP-C, Ubiquinol-cytochrome c reductase complex 14 kDa protein, Cytochrome b-c1 complex subunit 7
• Note: Molecular Weight: 13530 Da

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease