VPS11 (C-term) Rabbit Polyclonal Antibody

CAT#: AP54514PU-N

VPS11 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

VPS11 Antibody (C-term) western blot analysis in K562 cell line lysates (35 ug/lane). This demonstrates the VPS11 antibody detected the VPS11 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 771-800 amino acids from the C-terminal region of human VPS11
• Specificity: This antibody detects RNF108 / VPS11 (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column; followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens vacuolar protein sorting 11 homolog (S. cerevisiae) (VPS11), transcript variant 1
• Database Link:
  Entrez Gene 55823 Human
• Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
• Synonyms: PP3476
• Note: Molecular Weight: 107837 Da

Reference Data

• Protein Families: Druggable Genome