Semaphorin 7a (SEMA7A) Mouse Monoclonal Antibody [Clone ID: MEM-150]

CAT#: BM108S

Semaphorin 7a (SEMA7A) mouse monoclonal antibody, clone MEM-150, Purified

Product Images

Surface staining of HPB-ALL human peripheral blood T cell leukemia cell line with anti-human CD108 (MEM-150) FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: MEM-150
• Applications: FC, IP, WB
• Recommended Dilution: Flow Cytometry: 4 µg/ml.
  Immunoprecipitation.
  Western Blot under non reducing conditions.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: HPB-ALL human T cell line
• Specificity: The antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  State: Purified
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Ion exchange chromatography; purity: > 95% (by SDS-PAGE)
• Database Link:
  Entrez Gene 8482 Human
• Background: CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors plexin C1 and b1 integrins.
• Synonyms: Semaphorin-7A, SEMAL, Semaphorin-L, Semaphorin-K1