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VC1457 Mouse Monoclonal Antibody [Clone ID: 2/166]
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Specifications
| Product Data | |
| Clone Name | 2/166 |
| Applications | ELISA |
| Recommended Dilution | ELISA. |
| Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | Vibrio cholerae extract. |
| Specificity | This antibody is specific for the alpha subunit of Cholera toxin. |
| Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide State: Ig Fraction State: Liquid IgM fraction |
| Concentration | 5.0 mg/ml |
| Purification | Ammonium Sulphate Precipitation |
| Background | The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. |
| Synonyms | ctxA, toxA, VC_1457, Cholera enterotoxin A chain |
| Reference Data | |
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