beta III Tubulin (TUBB3) (N-term) Mouse Monoclonal Antibody [Clone ID: TU-20]

CAT#: BM170F

beta III Tubulin (TUBB3) (N-term) mouse monoclonal antibody, clone TU-20, FITC


USD 320.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name TU-20
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution Immunohistochemistry on Frozen and Paraffin Sections.
Immunocytotochemistry on Fixed and Permeabilized cells.

Suggested working dilution is 1/40.
The conjugate was also successfully used on FFPE Sections using Confocal Microscopy.
The unconjugated antibody (BM170S/BM170) also works for:
Flow cytometry.
ELISA.
Western Blot.
Immunocytochemistry.
Reactivities All Species
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide
Specificity This antibody recognizes the C-terminal peptide sequence ESESQGPK (aa 441-448) of human class III β-tubulin specific for neurones. The antibody is a highly specific marker for neuronal tissue. TU-20 is very useful for the detection of microtubule structures on fixed cells.
MAb TU-20 is widely cross-reactive among species (recognized epitope conserved within all species).
Formulation PBS containing 15 mM Sodium Azide as preservative, approx. pH 7.4
Label: FITC
State: Liquid purified Ig fraction
Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated FITC.
Concentration 1.0 mg/ml
Conjugation FITC
Background The betaIII-tubulin isotype is present dominantly in cells of neuronal origin and it is one of the earliest marker of neuronal differentiation. Class III beta-tubulin, is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The neuron-associated class III beta-tubulin isotype is most abundant in cells of neuronal origin but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
Synonyms Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.