CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: MEM-188]

CAT#: BM2401APC

CD56 (NCAM1) mouse monoclonal antibody, clone MEM-188, APC

Product Images

Surface staining of human peripheral blood lymphocytes with anti-CD56 (MEM-188) APC.

Specifications

Product Data

• Clone Name: MEM-188
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
• Reactivities: Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: KG-1 human acute myelogenous leukaemia cell line
• Specificity: The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
• Formulation: Phosphate buffered saline (PBS) solution containing 15mM sodium azide
  Label: APC
  State: Liquid purified IgG fraction
• Purification: Size-Exclusion Chromatography
• Conjugation: APC
• Storage: Store the antibody undiluted at 2-8°C
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 4684 Human
• Background: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
• Synonyms: NCAM-1, N-CAM-1, NCAM
• Note: The content of a vial (1 ml) is sufficient for 100 tests.