Hepatitis B Surface Antigen / HBsAg (adw/ayw) Mouse Monoclonal Antibody [Clone ID: S35]

CAT#: BM3319

Hepatitis B Surface Antigen / HBsAg (adw/ayw) mouse monoclonal antibody, clone S35, Purified

Specifications

Product Data

• Clone Name: S35
• Applications: ELISA, EM, IF, IHC
• Recommended Dilution:

  ELISA
  Immunofluorescent.
  Immunoperoxidase staining.
  Immunoelectron Microscopy.

• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: HBsAg purified from Human sera pool.
  Source: Ascites.
• Specificity: Recognizes HBsAg antigen (Adw/ayw).
• Formulation: PBS, pH 7.2 without preservatives.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A Sepharose Chromatography.
• Storage: Store the antibody undiluted at 2-8°C for one month or at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
• Synonyms: HBV surface antigen, Hepatitis B Virus