Hepatitis B Surface Antigen / HBsAg Mouse Monoclonal Antibody [Clone ID: HB5]

CAT#: BM3321

Hepatitis B Surface Antigen / HBsAg mouse monoclonal antibody, clone HB5, Purified

Specifications

Product Data

• Clone Name: HB5
• Applications: ELISA
• Recommended Dilution: Detection of HBsAg in two-site enzyme Immunoassay.
  Use this antibody as Capture in ELISA and BM3320 for Detection.
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant HBsAg of ayw subtype.
• Specificity: Hepatitis B virus surface antigen.
  Reacts with the following HBsAg subtypes: ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-, ayw3 (Fer).
• Formulation: PBS, pH 7.4 with 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction (>95% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Protein G Chromatography.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Background: Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
• Synonyms: HBV surface antigen, Hepatitis B Virus