Insulin (INS) Mouse Monoclonal Antibody [Clone ID: IN-05]

CAT#: BM4073S

Insulin (INS) mouse monoclonal antibody, clone IN-05, Purified

Specifications

Product Data

• Clone Name: IN-05
• Applications: ELISA, FN, IHC, R
• Recommended Dilution: ELISA.
  RIA.
  Immunocytochemistry.
  Functional Application.
  Immunohistochemistry on Paraffin Sections.
• Reactivities: Bovine, Human, Porcine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Porcine Insulin
• Specificity: The antibody reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas; it is also present in tumors of B cell origin such as insulinoma.
  The antibody IN-05 blocks binding of Insulin to the receptor.
• Formulation: Phosphate buffered saline (PBS), pH~7.3 with 15 mM Sodium Azide as presrevative.
  State: Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 3630 Human
• Background: Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.
• Synonyms: INS