Tfrc Rat Monoclonal Antibody [Clone ID: ER-MP21]

CAT#: BM4087LE

Tfrc rat monoclonal antibody, clone ER-MP21, Low Endotoxin

Specifications

Product Data

• Clone Name: ER-MP21
• Applications: FC, FN, IP
• Recommended Dilution: Immunoprecipitation.
  Functional Assays.
  Flow Cytometry: 1/50 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1.2.3 myeloma cell line.
• Specificity: This antibody recognises murine CD71, a 200kD antigen which is otherwise known as transferrin receptor.
• Formulation: PBS, pH 7.4
  State: Low Endotoxin
  State: Liquid purified IgG
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography on Protein G
• Database Link:
  Entrez Gene 22042 Mouse
• Background: CD71 is expressed by all proliferating cell populations and exists as a homodimer at the cell surface. Clone ER-MP21 inhibits iron uptake and cell proliferation but does not compete with transferrin for binding to its receptor, which suggests that clone ER-MP21 binds to an epitope that is different from the transferrin-binding site.
• Synonyms: TfR1, p90, Transferrin receptor protein 1