Iba1 (AIF1) Mouse Monoclonal Antibody [Clone ID: 1022-5]

CAT#: BM4114B

Iba1 (AIF1) mouse monoclonal antibody, clone 1022-5, Biotin

Product Images

Figure 1. AIF1 antibody staining of Human Spleen Paraffin Section.

Specifications

Product Data

• Clone Name: 1022-5
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml (1/40).
  Pretreatment is not necessary.
  Suggested Positive Control: Human spleen.
  This antibody does not react on routinely processed Frozen Sections.
• Reactivities: Human, Porcine, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified Human recombinant AIF-1
  Epitope is not further characterized.
• Specificity: Recognizes AIF-1.
  This antibody BM4114B reacts with activated Macrophages / Microglial cells.
• Formulation: PBS containing 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as a preservative.
  Label: Biotin
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore by adding 0.5 ml distilled water.
• Concentration: 0.2 mg/ml
• Purification: Affinity Chromatography.
• Conjugation: Biotin
• Storage: Store the original vial at 2-8°C, stock solution or aliquots thereof at -20°C.
  Avoid repeated thawing and freezing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 199 Human
• Background: Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated
  with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of
  pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.
• Synonyms: AIF-1, Protein G1, IBA1, Allograft inflammatory factor 1