Iba1 (AIF1) Mouse Monoclonal Antibody [Clone ID: 1022-5]

CAT#: BM4114F

Iba1 (AIF1) mouse monoclonal antibody, clone 1022-5, FITC

Specifications

Product Data

• Clone Name: 1022-5
• Applications: FC, IHC
• Recommended Dilution: Has been described to work in FACS and Immunohistochemistry on Paraffin Sections.
• Reactivities: Human, Porcine, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified Human recombinant AIF-1.
  Epitope not further characterized.
• Specificity: The antibody reacts with AIF-1.
• Formulation: PBS, pH 7.2
  Label: FITC
  State: Liquid purified IgG fraction
  Stabilizer: 10 mg/ml BSA
  Preservative: 0.09% Sodium Azide
• Concentration: 0.4 mg/ml
• Purification: Affinity Chromatography
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
  
  
• Gene Name: Homo sapiens allograft inflammatory factor 1 (AIF1), transcript variant 3
• Database Link:
  Entrez Gene 29427 RatEntrez Gene 199 Human
• Background: Allograft Inflammatory Factor-1 is a Ca²⁺-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca²⁺-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.
• Synonyms: AIF-1, Protein G1, IBA1, Allograft inflammatory factor 1

Reference Data

• Protein Families: Druggable Genome