Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 52) Mouse Monoclonal Antibody [Clone ID: 76.3]

CAT#: BM5011

Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 52) mouse monoclonal antibody, clone 76.3, Purified

Specifications

Product Data

• Clone Name: 76.3
• Applications: IF, IP
• Recommended Dilution: Immunofluorescence Microscopy: 1/10.
  Immunoprecipitation.
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant AAV-2 Rep78 protein, N-terminally truncated by 171 aa
• Specificity: Four Replicase proteins (Rep78, Rep68, Rep52 and Rep40) are expressed in different concentrations during infection. Antibody clone 76.3 reacts with Rep proteins (Rep78 and Rep52) of Human AAV-2-infected cells.
  It does not react with Rep68 and Rep40.
• Formulation: Final solution contains PBS, pH 7.4 with 0.09% Sodium Azide as preservative and 0.5% BSA as stabilizer
  State: Purified
  State: Lyophilized purified Ig fraction
• Reconstitution Method: Restore with 1.0 ml distilled water.
• Purification: Protein A Affinity Chromatography
• Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Serotype 2 (AAV2) has been the most extensively examined so far. AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes.
• Synonyms: AAV-2