KRT13 Mouse Monoclonal Antibody [Clone ID: 1C7]

CAT#: BM5047S

KRT13 mouse monoclonal antibody, clone 1C7, Supernatant

Specifications

Product Data

• Clone Name: 1C7
• Applications: IF, IHC, WB
• Recommended Dilution: Immunoblotting.
  Immunofluorescence.
  Immunohistochemistry on Frozen Sections: 1/5-1/25, preferable in PBS.
  Immunohistochemistry on Paraffin Sections: 1/10 after TUF treatment.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Cytokeratin purified from Human esophagus
• Specificity: This Monoclonal Antibody Clone 1C7 does stain non-cornifying squamous epithelium.
  In Immunoblotting experiments the antibody recognizes only Keratin 13 (54kD) and does not show any cross reactivity with other keratins.
  The antibody is a useful Marker for histopathology.
  Frozen sections give excellent results in immunoperoxidase and immunofluorescence tests.
  Cross reactivity:
  Vimentin : not detectable
  Desmin : not detectable
  GFAP : not detectable
  Neurofilament : not detectable.
• Formulation: State: Supernatant
  State: Liquid Culture Supernatant
  Preservative: 10mM Sodium Azide, FCS
• Storage: Store the antibody undiluted at 2-8°C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: keratin 13
• Database Link:
  Entrez Gene 3860 Human
• Background: Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
• Synonyms: CK-13, CK13, Keratin-13, KRT13, K13, KRT-13