Her2 (ERBB2) Mouse Monoclonal Antibody [Clone ID: CB11]

CAT#: BM5084

Her2 (ERBB2) mouse monoclonal antibody, clone CB11, Supernatant

Specifications

Product Data

• Clone Name: CB11
• Applications: IF, IHC, R, WB
• Recommended Dilution: RIA.
  Immunoblotting.
  Immunocytochemistry.
  Immunohistochemistry on Frotzen Sections.
  Immunohistochemistry on Paraffin-Embedded Sections (No pretreatment required).
  Recommended Dilutions: 1/5-1/10 for Immunohistochemistry.
  Recommended Positive Control: Adenocarcinoma of the breast.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (internal domain of the c-erbB-2 oncoprotein)
• Specificity: This Monoclonal CB11 antibody reacts with the 185 kD protein in Immunoblotting.
• Formulation: PBS
  State: Supernatant
  State: Liquid Culture Supernatant
  Stabilizer: 1% BSA
  Preservative: 0.09% Sodium Azide
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 2064 Human
• Background: The c-erbB2 proto-oncogene codes for a membrane protein. Several studies report the ampli-fication in carcinomas. Overexpression of c-erbB-2 in breast cancer is a marker for poor prognosis.
• Synonyms: HER-2, NEU, p185erbB2, NGL, c-erbB-2, MNL19