IGF1 Mouse Monoclonal Antibody [Clone ID: M23/ILG1-001]

CAT#: BM509

IGF1 mouse monoclonal antibody, clone M23/ILG1-001, Purified

Specifications

Product Data

• Clone Name: M23/ILG1-001
• Applications: ELISA, R
• Recommended Dilution: ELISA (1/10,000-1/100,000).
  Radioimmunoassays.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Biosynthetic IGF-1.
• Specificity: This antibody clone M23/ILG1-001 is specific for IGF-I. It shows minimal cross-reactivity with IGF-II, Proinsulin, MSF and Insulin.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens insulin like growth factor 1 (IGF1), transcript variant 3
• Database Link:
  Entrez Gene 3479 Human
• Background: Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
• Synonyms: IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer