Lamin A (LMNA) Mouse Monoclonal Antibody [Clone ID: X67]
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Specifications
Product Data | |
Clone Name | X67 |
Applications | IF, IHC, WB |
Recommended Dilution | Immunoblotting (Western). Immunofluorescence Microscopy. Immunohistochemistry: Ready-to-use. |
Reactivities | Bovine, Human, Xenopus |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells). |
Specificity | The monoclonal antibody cocktail decorates the karyoskeleton, i.e. the intermediate filament equivalent of the nucleus. Reacts with Lamin isotypes of Mr 60-75 kD. Xenopus laevis: LA, LI, LII Bovine: LA, C Mouse: n.d. Rat: - Human: LA, C Trout: LA, LI, LII Rat kangaroo: - |
Formulation | State: Supernatant State: Hybridoma Culture Supernatant containing 0.09% Sodium Azide as preservative. |
Storage | Store the antibody undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens lamin A/C (LMNA), transcript variant 2 |
Database Link | |
Background | Lamins do not appear to be universally distributed among different cell and tissue types. |
Synonyms | LMNA, LMN1, 70 kDa Lamin, NY-REN-32, NYREN32, Lamin-A/C, Lamin A, Lamin A + C, Nuclear Envelope Marker |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
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