Dopamine D2 Receptor (DRD2) (long isoform, 243-254) Rabbit Polyclonal Antibody

CAT#: BP121S

Dopamine D2 Receptor (DRD2) (long isoform, 243-254) rabbit polyclonal antibody, Serum


USD 620.00

2 Weeks*

Size
    • 100 ul

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Other products for "DRD2"

Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommended Dilution Immunocytochemical detection of the D2L dopamine receptor : this antiserum has been found to be stain specific cells in various regions of PLP fixed rat brain sections. This includes Medial septum, Nucleus accumbens, Dentate gyrus, Globus pallidus, Medial forebrain bundle, Cortex regions 1-3, Substantia Nigra reticulata, and the Ventral tegmental area.
Western immunoblots using whole rat brain homogenate resulted in a single band being detected at ~51 kD at 1:400 dilution.
Reactivities Human, Rat
Host Rabbit
Clonality Polyclonal
Immunogen D2L (243-254) cyclized covalently attached to a carrier protein.
Specificity Specific for D2L Dopamine Receptor (a.a. 243-254)cyclized. This antisera has been characterized by immunocytochemical, Western immunoblot and ELISA techniques.
Cross-reactivity:
D2L Dopamine Receptor (243-254)cyclized 100%
D2 Dopamine Receptor ~50%
D1 Dopamine Receptor (9-21) 0%
D1 Dopamine Receptor 0%
D3 Dopamine Receptor (2-10) 0%
D3 Dopamine Receptor 0%
D4 Dopamine Receptor (176-185) 0%
D4 Dopamine Receptor 0%
D5 Dopamine Receptor (23-35) 0%
D5 Dopamine Receptor 0%
Formulation State: Serum
State: Lyophilized neat serum without stabilizers and preservatives.
Reconstitution Method Reconstitute with 0.1 ml of PBS which contains 10 mg/ml BSA or with additional buffer for more dilute antisera.
Storage Lyophilized: Store at 2-8°C (preferably in a dessicator).
Reconstituted: Aliquot and store at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens dopamine receptor D2 (DRD2), transcript variant 1
Background The dopamine D2 receptor belongs to the G-protein coupled receptor 1 family and inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms, a short and a long isoform.
Synonyms DRD2
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Gap junction, Neuroactive ligand-receptor interaction

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