Mycobacterium tuberculosis (all antigens) Rabbit Polyclonal Antibody

CAT#: BP2027HRP

Mycobacterium tuberculosis (all antigens) rabbit polyclonal antibody, HRP

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: Suitable for immunohistochemistry and IFA.
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Purified PPD
• Specificity: Minimum of 2 major M. tuberculosis bands by immunoelectrophoresis (gamma & beta). This antiserum has not been absorbed and may react with related species. Reactive with other Mycobacteria species including M. avium, M. phlei and M. parafortuitum. Antibody is non-reactive with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitidis.
• Formulation: PBS containing 10 mg/ml BSA as stabilizer and 0.002 % Thimerosal as preservative.
  Label: HRP
  State: Liquid purified Ig fraction.
  Label: Purified IgG fraction covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed
  Molar radio: HRP: IgG substitution is 2-3
• Concentration: lot specific
• Conjugation: HRP
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliqquots) at -20°C for longer.
  Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
• Stability: Shelf life: one year from despatch.
• Background: Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
• Synonyms: M. tuberculosis, TB