Hepatitis B Surface Antigen / HBsAg (ad/ay) Rabbit Polyclonal Antibody

CAT#: BP2029B

Hepatitis B Surface Antigen / HBsAg (ad/ay) rabbit polyclonal antibody, Biotin

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: Avidin and streptavidin amplification systems for ELISA.
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay
• Specificity: Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. This antibody is non-reactive with normal human serum.
• Formulation: 10 mM PBS pH 7.2 with 0.09% sodium azide as preservative and no stabilizing proteins.
  Label: Biotin
  State: Liquid purified Ig fraction.
  Label: IgG fraction is covalently coupled with the N-Hydroxysuccinimide ester of under mild conditions to give a high degree of substitution
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Background: Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
• Synonyms: HBV surface antigen, Hepatitis B Virus