Apolipoprotein CI (APOC1) Goat Polyclonal Antibody

CAT#: BP2082HRP

Apolipoprotein CI (APOC1) goat polyclonal antibody, HRP

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: Can be used for detection of Apo CI in plasma and lipoproteins.
  Immunoassay and Western blots (dilution 1:1,000 - 1:4,000).
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Specificity: Binds to human Apo CI.
  No cross reactivity with other human plasma apoproteins.
• Formulation: 50 mM PBS, pH 7.4 containing 0.1 M Sodium Chloride and 10 mg/ml BSA as stabilizer and 0.01 % Thimerosal as preservative.
  Label: HRP
  State: Lyophilized purified Ig fraction
  Label: Conjugated to Horseradish peroxidase
• Concentration: lot specific
• Purification: Immunoaffinitty by Human Apo CI Sepharose column.
• Conjugation: HRP
• Storage: Prior to reconstitution store the antibody at 2-8 °C.
  Following reconstitution store undiluted at 2-8 °C for one month or at -20°C for longer.
  This product is photosensitive and should be protected from light. Should it contain a precipitate we recommend microcentrifugation before use.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 341 Human
• Background: The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.
• Synonyms: Apolipoprotein C-I, Apolipoprotein C1, Apo-CI, ApoC-I