SQSTM1 (C-term) Guinea Pig Polyclonal Antibody

CAT#: BP5002

SQSTM1 (C-term) guinea pig polyclonal antibody, Serum


USD 405.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western blotting: 1/1000-1/2000 (ECL).
Immunohistochemistry on Frozen Sections: 1/100-1/600.
Immunohistochemistry on Paraffin Embedded Sections: 1/100-1/600 (microwave pretreatment improves staining).
Incubation time: 1h at RT, extended with paraffin material.
Reactivities Human, Mouse, Rat
Host Guinea Pig
Clonality Polyclonal
Immunogen C-terminal domain (20 amino acids: C-NYD IGA ALD TIQ YSK HPP PL) of Human p62 protein, coupled to KLH.
Specificity This antibody reacts with Human 62 kD (p62) protein, present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein (also described as ubiqutin-binding protein; sequestosome 1, SQSTM1) has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism (e.g. ubiquitin-associated degradation and autophagy). 
The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimer's disease.
Formulation State: Serum
State: Liquid Stabilized Antiserum
Preservative: 0.09% Sodium Azide
Gene Name Homo sapiens sequestosome 1 (SQSTM1), transcript variant 2
Synonyms Sequestosome-1, EBIAP, ORCA, OSIL, p60, p62
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.