SQSTM1 (N-term) Guinea Pig Polyclonal Antibody

CAT#: BP5003

SQSTM1 (N-term) guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blotting: 1/1000 (ECL).
  Immunohistochemistry on Cytological material.
  Immunohistochemistry on Frozen Sections: 1/100.
  Immunohistochemistry on Paraffin Sections: 1/100 (microwave treatment improves staining).
  Incubation Time: 1 h at RT, extended with paraffin sections.
• Reactivities: Human, Rat
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: N-terminal domain (20 amino acids: MAS LTV KAY LLG KED AAR EI-C) of Human p62 protein, coupled to KLH
• Specificity: This antibody reacts with Human 62 kD (p62) protein, present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism.
  The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimers disease.
  Negative Species: Mouse.
• Formulation: State: Serum
  State: Liquid Stabilized Antiserum
  Preservative: 0.09% Sodium Azide
• Gene Name: Homo sapiens sequestosome 1 (SQSTM1), transcript variant 2
• Database Link:
  Entrez Gene 113894 RatEntrez Gene 8878 Human
• Synonyms: Sequestosome-1, EBIAP, ORCA, OSIL, p60, p62

Reference Data

• Protein Families: Druggable Genome, Transcription Factors