Cytokeratin 19 (KRT19) Guinea Pig Polyclonal Antibody

CAT#: BP5020

Cytokeratin 19 (KRT19) guinea pig polyclonal antibody, Serum


USD 390.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommended Dilution ELISA. 
Western blot (1/3000, ECL).
Cytological material. 
Immunocytochemistry/Immunofluorescence: 1/100.
Immunohistochemistry on Frozen Sections: 1/200.
Immunohistochemistry on Paraffin Embedded Tissues: 1/100 (Microwave treatment recommended).
Incubation Time: 1 h at RT (extended with paraffin sections).
Reactivities Bovine, Human
Host Guinea Pig
Clonality Polyclonal
Immunogen Human Keratin 19, purified from MCF-7 cells
Specificity Reacts with acidic Keratin 19 (Mr 40,000) (formerly also designated Cytokeratin 19).
Tumors Specifically detected: All adeno-Ca tested.
The antiserum represents an excellent marker for all glandular type epithelia, useful for discrimination of glandular epithelial carcinoma from those of different origin.
No reaction with hepatocellular carcinoma!
Formulation State: Serum
State: Liquid Stabilized Antiserum
Stabilizer: 0.5% BSA
Preservative: 0.09% Sodium Azide
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
Synonyms Cytokeratin-19, Keratin-19, KRT19, CK19, K19
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.