pan Cytokeratin Rabbit Polyclonal Antibody

CAT#: BP5070

pan Cytokeratin rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin-Embedded Tissue (Proteolytic treatment with Trypsin is recommended).
  Working Dilution: 1/50 (optimize by serial dilution).
  Dilution Buffer: Dilute immediately before use with PBS or TBS.
  Incubation time: 1 h at room temperature.
  Recommended Positive Control: Squamous cell carcinoma, skin, cervix.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Human skin.
• Specificity: This antibody reacts positively with all stratified squamous epithelia and epidermal appendages such as hairfollicles, sebaceous glands. Also positive on epithelia of the urinary tract, stomach, intestine, uterine endometrium and prostate. Identifies mesotheliomas, squamous cell carcinomas, adenocarcinomas, transitional cell carcinomas and anaplastic carcinomas.
• Formulation: PBS or TBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Purification: Affinity Chromatography
• Background: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
• Synonyms: pan Keratin, Cytokeratin pan-reactive